Spravato® Therapy in Bellevue | SageMED

What Is Spravato®?

Spravato® is a prescription nasal spray containing esketamine, a form of ketamine. It is FDA-approved for:

• Treatment-Resistant Depression (TRD) in adults
• Major Depressive Disorder (MDD) with suicidal thoughts or behavior in adults when used in combination with an oral antidepressant

Spravato® is different from standard antidepressants in how it acts in the brain and is delivered under medical supervision. A consultation helps determine whether Spravato® is an appropriate option based on diagnosis and treatment history.

How Does Spravato® Therapy Work?

Spravato® targets the brain’s glutamate system, which plays a role in neural signaling and mood regulation. By influencing glutamate pathways, Spravato® may support changes in brain connectivity associated with depression symptoms.

At SageMED, Spravato® is administered in-office. After dosing, patients remain in our clinic for a two-hour observation period to monitor for side effects and ensure safety. During this time, patients can rest, listen to music, or use our clinic’s Wi-Fi.

Conditions Treated by Spravato® Therapy

Spravato® therapy is used for:

• Treatment-Resistant Depression (TRD)
• Major Depressive Disorder (MDD) with suicidal thoughts or behavior

In clinical studies, Spravato® used with an oral antidepressant showed greater symptom improvement than placebo plus an oral antidepressant in appropriate patients. Results vary and depend on individual factors.

Spravato® Treatment Schedule

Many patients begin with:

• Twice weekly for the first 4 weeks
• Followed by a tapering schedule based on progress and clinical guidance

After each session, patients are observed for two hours in the clinic. You will need to arrange transportation home, as you cannot drive post-treatment.

Is Spravato® Right for You?

Spravato® therapy may be appropriate for adults who:

• Have TRD (often defined as inadequate response to at least two antidepressants), or
• Have MDD with suicidal thoughts or behavior, and
• Are appropriate candidates for in-office supervised treatment

To determine if Spravato® is right for you, schedule a consultation with Dr. David Deichert at SageMED.

Potential Side Effects of Spravato® Therapy

Most side effects occur during the observation period and tend to resolve the same day. Possible side effects may include:

• Dissociation
• Dizziness
• Nausea or vomiting
• Anxiety
• Fatigue or drowsiness
• Increased blood pressure
• Euphoria or “spinning” sensation
• Numbness or tingling

Most patients find side effects manageable with monitoring and supportive care, but experiences vary. Your clinician will review risks and safety considerations during consultation.

Frequently Asked Questions (FAQs)

What are the potential side effects?

Most side effects occur during the two-hour observation window and can include dissociation, dizziness, nausea, sleepiness, and temporary increases in blood pressure. Effects often resolve the same day.

Is Spravato® covered by insurance?

Spravato® is commonly covered by many insurance plans, often with prior authorization. Our team can help verify coverage and assist with the authorization process.

How quickly will I see results?

Some patients report improvement early in treatment, sometimes within the first few sessions, while others take longer. Significant symptom relief is often evaluated over several weeks. Response varies.

What age groups can use Spravato®?

Spravato® is approved for adults aged 18 and older.

How long does each appointment take?

You will remain in the clinic for two hours after dosing for required monitoring. Total visit time may be longer depending on check-in and clinical workflow.

Why can’t I drive after treatment?

Spravato® can cause temporary dissociation, drowsiness, or dizziness. For safety, you must arrange transportation home after each session.

Is Spravato® the same as ketamine?

Spravato® contains esketamine (a form of ketamine) and is administered under a structured medical program with required monitoring. A clinician can discuss differences and appropriateness based on your history.

Why Choose SageMED for Spravato® Therapy?

As a trusted integrative health clinic in Bellevue serving the Greater Seattle area, SageMED provides clinician-guided care for patients seeking options for severe depression.

• Care led by Dr. David Deichert
• In-office administration with required monitoring for safety
• Personalized planning with support throughout the treatment course
• A professional setting designed for privacy and patient comfort

Schedule Your Spravato® Consultation Today

If you are struggling with treatment-resistant depression or MDD with suicidal thoughts or behavior, Spravato® therapy may be an option worth exploring. Contact SageMED today to schedule a consultation with Dr. David Deichert and discuss whether Spravato® treatment is a fit.