Spravato® (esketamine) is the first FDA-approved nasal spray for adults with Treatment-Resistant Depression.

 

What is Spravato® ?

Spravato® is an esketamine nasal spray derived from ketamine. More potent than ketamine, Spravato® can be used safely at lower doses than traditional ketamine treatment with fewer side effects.₁ Spravato® is the first and only esketamine nasal spray approved by the FDA, and positive effects are often felt after the first or second treatment.

Spravato® treatments are administered in-office, and patients stay in the treatment room for observation for two hours after the spray is administered. During this observation time, most patients prefer to relax. You are free to bring some headphones and listen to music, watch a movie, or get some work done using our free clinic WiFi if you would like.

What Conditions Does Spravato® Treat?

Spravato® is FDA-approved to treat Treatment Resistant Depression (TRD) and Major Depressive Disorder (MDD) that occurs in combination with suicidal thoughts or actions. Given in conjunction with an oral anti-depressant, Spravato® has been shown to have a greater reduction on depressive symptoms after four weeks of treatment compared to a placebo and antidepressant combination₂.

Is Spravato® Right for Me?

Folks who have TRD or MDD with suicidal thoughts and have failed to improve after trying at least two antidepressants are typically eligible for Spravato®. To learn if Spravato® is right for you and discuss any questions you may have, schedule a new patient visit with Dr. David Deichert below.

 

FAQ

  • The majority of side-effects occur during the two hour observation period immediately after treatment. Side effects can include:

    • Dissociation

    • Dizziness

    • Nausea

    • Anxiety

    • Feeling tired or lethargic

    • Increased blood pressure

    • Vomiting

    • Feelings of euphoria

    • Spinning sensation

    • Numbness

  • Spravato is typically covered by Medicare and most insurance plans. After your initial visit, our clinical team will work with your insurance company to obtain prior authorization for treatment.

    Once authorization is obtained, we will contact you to schedule treatment. You will not be able to drive after your Spravato treatment and observation, and will need to coordinate alternative transportation.

  • At this time, Spravato is only available for folks 18 and older.