Collagen P.I.N.® Microneedling with EXO|E™ Exosomes

What Is Collagen P.I.N.® Microneedling?

Collagen P.I.N.® microneedling creates controlled micro-channels that trigger the skin's natural repair response. Over time, this supports gradual renewal that may improve the appearance of uneven texture, tone irregularities, fine lines, enlarged pores, and acne scars.

What Is the EXO|E™ Add-On?

EXO|E™ is a topical system that includes plant-derived extracellular vesicles and skin-supportive components used after microneedling as an aesthetic adjunct. At SageMED in Bellevue, it is offered as an optional add-on for patients who want a more supported recovery phase and enhanced cosmetic skin revitalization.

Important note: EXO|E™ is used for cosmetic skin renewal goals and is not positioned as a disease treatment.

How Collagen P.I.N.® Microneedling Works

The Collagen P.I.N. device uses a 36-pin needle cartridge that glides across the skin to create tiny micro-channels. These controlled micro-injuries stimulate the body's natural healing cascade, encouraging the regeneration of new skin cells and supporting the remodeling of damaged tissue.

This process can be especially helpful for concerns such as acne scarring, rough texture, and uneven pigmentation, while maintaining the skin's natural structure.

Comfort-focused and personalized depth

Before treatment, a topical numbing cream is applied to improve comfort. Your SageMED clinician then selects the appropriate needle depth based on the thickness and sensitivity of each treatment area. This allows for a personalized approach, including:

• More delicate areas, such as around the eyes
• Thicker areas, such as the jawline, neck, or select body regions

What the micro-channels can support

Because microneedling creates temporary micro-channels, clinicians may apply topical skin-supportive products immediately after treatment to support hydration and comfort. At SageMED, EXO|E™ can be used as an advanced topical add-on, selected to support the skin's recovery phase and overall renewal.

Collagen P.I.N.® Treatment Areas

Collagen P.I.N. microneedling is versatile and can be used on multiple areas of the face and body, including:

• Face
• Neck and décolleté
• Hands
• Acne scars on the face and body
• Stretch marks on the abdomen, thighs, and other areas

Who Is a Good Candidate?

Collagen P.I.N. microneedling may be a good option if you want to improve:

• Acne scars or uneven texture
• Uneven tone and dull-looking skin
• Fine lines and early wrinkles
• Visible pores and rough skin texture
• Stretch marks in select areas

You may be a good candidate if you:

• Want a non-surgical treatment with a relatively quick recovery window
• Prefer an approach that can be tailored by treatment area and skin sensitivity
• Are comfortable with a series-based plan when needed for scarring or texture goals

A proper evaluation is important. At SageMED, candidacy is determined through a consultation that reviews your skin concerns, medical history, and overall treatment goals. In some cases, your clinician may recommend delaying treatment if your skin needs stabilization before microneedling.

What to Expect During Your Collagen P.I.N.® Treatment

Step 1: Consultation

Your visit begins with a consultation to assess your skin, discuss your goals, and determine whether Collagen P.I.N. microneedling is the right option. You'll also review anticipated downtime, aftercare, and how many sessions may be appropriate.

Step 2: Numbing and Preparation

A topical numbing cream is applied for approximately 30 to 60 minutes to minimize discomfort. Your skin is then cleansed and prepared so the device can glide smoothly and evenly across the treatment area.

Step 3: Treatment Application

The Collagen P.I.N. 36-pin cartridge is used to create thousands of precise micro-channels in the skin. Needle depth is adjusted based on the treatment zone and your individual skin needs. Some patients choose to pair treatment with hydrating topical serums to support post-treatment comfort.

After microneedling, EXO|E™ is applied topically as part of the post-procedure protocol. Your clinician will guide product timing and whether an at-home sequence is appropriate for your skin goals and sensitivity.

Step 4: Post-Treatment Care

Mild redness is common after microneedling and may resemble a light sunburn. This typically settles within a short period for most patients. Your SageMED clinician will provide personalized aftercare recommendations to help minimize redness, dryness, or flaking over the next few days.

Results and How Long They Last

Collagen P.I.N. microneedling results develop gradually as the skin repairs and remodels. Many patients notice early improvements in texture and overall glow as the skin heals, with continued improvement over the following weeks.

What many patients can expect:

• Early changes within the first one to two weeks
• Progressive improvement as collagen remodeling continues
• More significant results for acne scars and stretch marks when treatments are performed as a series

Results vary based on factors such as scar depth, skincare routine, sun exposure, and individual healing response.

Benefits of Collagen P.I.N.® Microneedling

Patients often choose Collagen P.I.N. microneedling for its balance of effectiveness, customization, and relatively quick recovery.

Safety, Downtime, and Aftercare

Collagen P.I.N. microneedling is generally well tolerated when performed by trained professionals. As with any treatment that affects the skin barrier, proper technique and aftercare are essential.

Common, temporary post-treatment effects

• Redness and warmth
• Mild swelling or tightness
• Dryness or light flaking over the next few days

Downtime expectations

Most patients experience temporary redness, warmth, and a sunburn-like sensation after microneedling, which typically improves over several days (and can last up to about a week for some). Your clinician will tailor aftercare based on the depth used and your skin's baseline sensitivity.

Aftercare guidance

Your SageMED clinician will provide personalized instructions, which typically emphasize gentle skincare, hydration, and consistent sun protection during recovery.

Important considerations

• Results are not guaranteed and vary by individual
• A medical and skin review is important to determine appropriate timing and candidacy
• If you experience worsening pain, spreading redness, or signs of infection, contact your care team

Frequently Asked Questions (FAQs)

How Many Treatments Will I Need?

Most patients notice visible improvements after their first session, with optimal results achieved after a series of three to six treatments spaced about four weeks apart. Your provider at SageMED will customize a treatment plan based on your individual skin concerns, such as deep wrinkles, stretch marks, or advanced sun damage.

How Long Will Results Last?

Results from Collagen P.I.N. microneedling are both immediate and long-lasting. Collagen and elastin production continues for several months after each treatment, with visible improvements lasting up to one year. Maintenance sessions every six to twelve months can help extend the benefits of treatment.

Does Collagen P.I.N. Microneedling Hurt?

The treatment is designed to be as comfortable as possible. With the use of a numbing agent, most patients report little to no discomfort during the session. Any redness or sensitivity typically resolves within a day, and mineral-based makeup can usually be applied the next day.

What makes this different from standard Collagen P.I.N.?

This option includes a clinician-applied EXO|E™ topical protocol immediately after microneedling, designed to support the recovery window and overall skin renewal experience.

Is downtime shorter with EXO|E™?

Recovery varies by needle depth, treatment area, and individual skin sensitivity. Microneedling commonly causes temporary redness and sensitivity for several days; your clinician will guide expectations based on your specific plan.

Who should not add EXO|E™?

If you have an active skin infection, uncontrolled inflammatory flare, or a history of poor wound healing, your clinician may recommend postponing or simplifying your protocol until the skin barrier is stable.

Why Choose Collagen P.I.N.® Microneedling at SageMED?

SageMED offers clinician-guided Collagen P.I.N. microneedling with a focus on personalized treatment depth, comfort, and evidence-informed care.

What sets SageMED apart:

• Experienced practitioners who tailor treatment depth by area and skin needs
• Advanced Collagen P.I.N. technology using a 36-pin cartridge for consistent coverage
• Personalized aftercare plans to support healing and optimize results
• Comfort-focused sessions designed to minimize discomfort and downtime

Whether you're addressing acne scars, fine lines, or uneven tone, SageMED in Bellevue builds a treatment plan aligned with your skin goals and recovery preferences.

When to Schedule a Consultation

If you're ready to improve skin texture, tone, or acne scarring with a clinician-guided approach, a consultation is the next step.

You may want to schedule a consultation if:

• You have persistent acne scarring or uneven texture you want to improve
• You want collagen-supporting results without aggressive resurfacing downtime
• You're unsure which skincare treatment best fits your skin type and goals
• You want a personalized plan with expert aftercare guidance

At SageMED, consultations focus on understanding your goals, evaluating your skin, and recommending the most appropriate treatment through shared decision-making.