Peyronie’s Disease: A Modern, Evidence-Informed Path to Recovery

Peyronie’s causes a severe and often painful bend in the penis

Peyronie’s disease (Penile Fibromatosis) is far more common, and far more treatable, than most men realize. It is characterized by the development of fibrous scar tissue, known as plaques, within the penis. This can lead to curvature, pain with erections, loss of length or girth, and significant emotional distress. For many men, the physical changes are only part of the burden. Confidence, intimacy, and overall quality of life are often affected. At our clinic, Peyronie’s disease is approached with seriousness, precision, and respect for how deeply it impacts a man’s life.

Stages of Peyronie’s (Penile Fibromatosis)


A Different Philosophy of Care

Peyronie’s disease is not just a localized structural issue. Tissue healing, inflammation, collagen remodeling, erectile function, and sexual performance are all influenced by systemic factors such as hormones, nutrient status, vascular health, and metabolic balance.

That is why every patient begins with a comprehensive evaluation, which includes:

  • A detailed physical and functional exam

  • Penile assessment and curvature analysis, with imaging when appropriate

  • Hormone evaluation, including testosterone, estradiol, SHBG, and thyroid markers

  • Nutrient and metabolic testing relevant to tissue repair and fibrosis

Before and during treatment, we correct hormone and nutrient deficiencies and address drivers of inflammation. Optimizing the internal environment first is one of the primary reasons our outcomes are consistently strong.

Our Multi-Modal Treatment Approach

Each treatment plan is customized. We combine advanced regenerative and mechanical therapies based on disease stage, severity, and individual anatomy.

Platelet-Rich Plasma (PRP) Injections

PRP is derived from your own blood and concentrated with growth factors that support tissue healing, angiogenesis, and collagen remodeling. When precisely injected into areas of plaque and dysfunction, PRP can help soften fibrotic tissue and improve erectile quality.

PRP injections (after numbing)

Focused Shockwave Therapy

We use focused shockwave therapy, not radial devices. Focused shockwaves deliver controlled acoustic energy deep into targeted tissue, helping to:

  • Reduce pain

  • Improve blood flow

  • Stimulate cellular repair

  • Enhance the effectiveness of regenerative injections

This therapy is a cornerstone of our protocol and plays a key role in improving both function and comfort.

Shockwave can soften plaque and improve blood flow

Traction and Vacuum Therapy

Mechanical therapies are used strategically to:

  • Promote restoration of length

  • Encourage plaque remodeling

  • Improve symmetry and straightness over time

When used correctly and paired with regenerative therapies, these tools significantly enhance results.

Custom Compounded Topical Therapies

We also utilize custom-formulated topical medications developed specifically for Peyronie’s disease. These are not generic creams. They are targeted compounds selected to support anti-fibrotic activity and local tissue healing.

Comfort Matters: Minimally Painful Procedures

Many men understandably worry about discomfort. Our procedures are designed to be very well tolerated. We use both topical anesthetics and a targeted local nerve block. Most patients describe treatment as minimally painful, and all procedures are performed in-office without sedation or downtime.

Outcomes That Matter to Men

While individual results vary, our internal clinical data are strong:

  • 100% of patients achieve pain-free erections

  • 92% experience restoration of size

  • 78% achieve a satisfactory reduction in curvature

  • 84% report being satisfied or very satisfied with their outcome

These are real-world results from men treated in our clinic, not projections or marketing claims.

Experience You Can Trust

As sexual health treatments become more mainstream, and the predictable wave of charlatans sell inferior or ineffective treatments, it is even more imperative to carefully vet your doctors. I want to assure you that I am passionate about what I do, and driven by continued success. I bring more than 15 years of experience in men’s health and regenerative injection therapies to this work.

  • I actively teach other physicians how to perform these treatments safely and effectively

  • I am a Key Opinion Leader for Alma Lasers in shockwave therapy and BioTE Medical in hormone optimization

  • I serve as an accredited residency site director, training the next generation of doctors

  • I lecture internationally on men’s health, aesthetics, and regenerative medicine

This approach is not experimental. It is refined, taught, and continuously improved through clinical practice and physician education.

Cost and Candidacy

  • Free consultations are offered to determine candidacy

  • Treatment costs range from $1,600 to $5,600, depending on severity and the amount of therapy required

We believe men deserve transparency, realistic expectations, and options that do not default to surgery or inaction.

Take the First Step

Peyronie’s disease does not have to define your future or your confidence. With the right combination of internal optimization and advanced regenerative care, meaningful improvement is possible.

If you are ready to explore your options, we invite you to schedule a free, no-obligation consultation with Dr. Sage Wheeler and have an honest, expert-level discussion about what can be done.

You are not alone, and you are not out of options.

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